Effects of acute hypoxia and furosemide on intracranial dynamics in conscious goat
- VernacularTitle:清醒山羊缺氧时的颅内动力学改变及速尿的影响
- Author:
Yingbo YANG
- Publication Type:Journal Article
- Keywords:
Goats;
Intracranial pressure;
Furosemide;
Anoxia
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
We have studied the effects of acute hypoxia and furosemide on intracranial dynamics in 15 conscious goats with a light water load. Eight goats were subjected to acute hypoxia (H group) and the remains, under the same hypoxic conditions, were injected with furosemide (F group). Hypoxia (simulated high altitude of 4000m for 2hr) obviously elevated the cerebral blood flow (CBF), the mean intracranial pressure (MICP) and the cerebral water content but reduced the intracranial compliance markedly. In contrast, no obvious differences was observed in all the above mentioned intracranial dynamic parameters in F group.
