The changes of spontaneous electrical activity of the vagus efferent nerve in scalded rats
- VernacularTitle:大鼠烫伤后迷走神经放电活动的变化
- Author:
Yafei ZHANG
- Publication Type:Journal Article
- Keywords:
Burns;
Vagus nerve
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Experiments were performed on Wistar rats under the anaesthesia of urethane. Rats were put in a slant box and subjected to a third-degree burn over 35 per cent of the body surface scalded by immersion of the hind half of the body, including the tail, in a water bath maintained at 70℃ for 15 sec. The spontaneous electrical activity of the central cut stump of cervical vagus nerve-trunk and single vagus fibers was recorded. The purpose of the present study is to evaluate the activity of the parasympathetic nerve in scalded rats. The discharge of the cervical vagus nerve (nerve—trunk or single fiber) increased immediately, showing continuous discharge with higher frequency in the first 30-90 sec after scalding and the rhythm synchronizing with the respiration disappeared. After that, the impulses of the vagus nerve reduced and lasted for 15-30 min, then the frequency of discharge increased and approximated to the control level. During the period 60-360 min after scalding, two kinds of discharge of the vagus nerve-trunk were observed. Discharging frequency of seven rats out of the ten decreased gradually, while the frequency of discharge in the rest three rats continuously increased. The pattern of discharge of the vagus nerve revealed that the discharge of some fibers was strengthend, while that in some other fibers weakened or disappeared. The results mentioned above suggested that an immediate and transient increase of the excitation of the vagus center was present, afterwards the excitation of some central neurones was increased, while that of some other central neurones was depressed.
