The effect of extracts of Alternaria alternata on nucleolus organizer region and cell proliferating cycle of lymphocytes
- VernacularTitle:互隔交链孢霉提取物对淋巴细胞核仁形成区及细胞增殖周期的影响
- Author:
Weihua DONG
- Publication Type:Journal Article
- Keywords:
Alternaria;
Mycotoxins;
Nucleolus organizer region;
Cell cycle;
Lymphocytes
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The authors have determined the effects of 261-B_2-3 and C_(12)b_3-2, extracts two strains of Alternaria alternata, on the nucleolus organizer regions (NORs) activity and the progression of cell proliferating cycle of human peripheral lymphocytes. The methods used in the experiment were selective silver staining of human NORs and cytophotometry. The result showed that the number of chromosomes bearing Ag-NORs was meaningly decreased when the cells were treated with different concentrations of 261-B_2-3 and C_(12)-b_3-2 extracts. The difference was quite significant when the data were compared with those of the control (P
