Effect of Tanshinone on human polymorphonuclear leucocyte chemokinesis
- VernacularTitle:丹参酮对人白细胞化学运动影响的观察
- Author:
Shufen WANG
- Publication Type:Journal Article
- Keywords:
Inflammation;
Leukocytes
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The paper studied effect of different doses of Tanshinone on human polymorphonuclear leucocyte chemokinesis by agarose microdroplet assay. The results indicate that more than 10ng/ml Tanshinone inhibites significantly human polymorphonuclear leucocyte chemokinetic response to 10~(-9)M FMLP. This inhibitory effect is probably one of mechanisms of Tanshinone anti-inflammatory activity. The agarose microdroplet assay is a reliable mothod for studying leucocyte chemokinesis in vitro.
