Research on reperfusion damage of shocked intestine: Ⅳ. Effect of cell protective agents on the reperfusion damage
- VernacularTitle:休克小肠再灌注损伤的研究:——Ⅳ.“细胞保护剂”对再灌注损伤的影响
- Author:
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Shock;
Vcrapamil;
Vitamin E.
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The comparison of effects of different cell protective agents on reperfusion damage was performed on the model rabbit's ischemic shock intestine. The result showed that anisodamine, glutatbione, vitamin E and verapamil at a certain extent had protective effects on reperfusion damage; and that hydrocortisone, mannitol and sodium pentobarbitate did not tave any effects on it; although indomethacin and humic acid did not improve intestinal reperfusion damage, they significantly alleviated the subendocardial damage after ischemic intestinal reperfuison; and that in contrast to the above agents, ATR-MgCl_2 deteriorated the reperfusion injury. The possible mechanisms of reperfusion damage were discussed in this article.
