In vivo effect of antiinflammatio No.6, streptomycin and chloromycetin on granulocyte migration in the rat
- VernacularTitle:抗炎6号、链霉素、氯霉素对大鼠中性粒细胞移动的影响
- Author:
Feili GONG
- Publication Type:Journal Article
- Keywords:
Neutrophils;
Chemotaxis;
Rats
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Daily i.v. injection of 4ml of the traditional Chinese medicine antiinflammatio No.6(AI6) to rats for 3 days resulted in a marked acceleration of chemotaxis (Cht) of neutrophil granulocytes(NG). Daily i.m. injection of streptomycin(SM) and chloromycetin(CM), each in a dose of 50mg per animal, given to rats for 3 days led to a marked depression of Cht of NG, while combined with daily i.v. injection of 4ml of AI6 caused not only a complete cancelling of the suppressive effect of the antibiotics on NG Cht, but also a marked acceleration of NG Cht. Combined application of AI6 and certain antibiotics in the clinical treatment of certain acute bacterial infections is suggested.
