1H-MRS measurement of the hippocampus in chronic obstructive pulmonary disease
10.3969/j.issn.1002-1671.2017.04.003
- VernacularTitle:慢性阻塞性肺疾病海马1H-MRS成像研究
- Author:
Cunqiang WANG
;
Xiying TAN
;
Yu WANG
;
Shunling HE
;
Yunze GU
;
Ziyang YUAN
- Keywords:
chronic obstructive pulmonary disease;
1H-magnetic resonance spectroscopy;
hippocampus
- From:
Journal of Practical Radiology
2017;33(4):500-502
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the features of 1H-magnetic resonance spectroscopy(1H-MRS) in patients with chronic obstructive pulmonary disease(COPD) of the hippocampus.Methods 32 patients with COPD randomly selected and 30 normal controls were selected.1H-MRS of the hippocampus was performed given to on all the subjects on hippocampus.The ratios of NAA/Cr and Cho/Cr were determined.Results In the bilateral hippocampus, the NAA/Cr ratio in patients with COPD demonstrated lower than that in normal controls(t=4.963,P=0.007 and t=4.856,P=0.023).The Cho/Cr ratio in patients with COPD showed higher than that in normal controls, the differences was were statistically significant(t=3.469,P=0.013 and t=3.019,P=0.047) Conclusion Abnormal metabolism of neurons on the hippocampus in patients with COPD is showed.
