Efficacy of ambroxol hydrochloride inhalation in treatment of infantile pneumonia
10.7501/j.issn.1674-6376.2017.02.024
- VernacularTitle:盐酸氨溴索雾化吸入治疗新生儿肺炎的疗效分析
- Author:
Wenhua ZHAO
;
Huiping WANG
- Keywords:
ambroxol hydrochloride;
atomizing inhalation;
pneumonia;
blood viscosity;
adverse reaction
- From:
Drug Evaluation Research
2017;40(2):255-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the efficacy of ambroxol hydrochloride inhalation in treatment of infantile pneumonia.Methods Totally 80 pneumonia infants were selected and randomly divided into two groups.The control group (39 cases) were given anti-infection,cough-relieved,and other treatment.The observation group (41 cases) were given ambroxol hydrochloride inhalation on the basis of control group treatment.The efficacy of ambroxol hydrochloride inhalation in treatment of infantile pneumonia was evaluated by efficacy,clinical symptoms disappearing time,red blood cell hematocrit,blood viscosity,and adverse reaction during treatment.Results After treatment,the effective rate of observation group was higher than that of control group (P ＜ 0.05).There were 38 infants in observation group and 28 infants in control group with cough and dyspnea alleviated and phlegm reduced.After atomizing inhalation of ambroxol hydrochloride,the cough,pulmonary rales disappearing time and hospitalization time were significantly shortened (P ＜ 0.05).After treatment,the red blood cell hematocrit and blood viscosity of observation group was lower than that of control group (P ＜ 0.05).During treatment,there was no statistical significance on adverse reaction between two groups.Conclusion Ambroxol hydrochloride inhalation has a good curative effect on infantile pneumonia.It could improve the symptoms of pneumonia and reduce blood viscosity with good safety,which is worthy of clinical use.
