Significance of Hypoxia-related microRNA for Estimating the Cause of Mechanical Asphyxia Death
10.3969/j.issn.1004-5619.2017.01.010
- VernacularTitle:缺氧相关microRNA在窒息死亡原因推断中的意义
- Author:
Yan ZENG
;
Jianlong MA
;
Long CHEN
- Keywords:
forensic pathology;
asphyxia;
review;
m icroR N A;
anoxia;
cause of death
- From:Journal of Forensic Medicine
2017;33(1):38-41
- CountryChina
- Language:Chinese
-
Abstract:
U nder hypoxia condition, m icroR N A (m iR N A ) can interact w ith transcription factors for regu-lating the cell m etabolism , angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. T he biological processes above m ay play an im portant role in m echanical asphyxia death. T his article re-view s the regulating function of m iR N A under hypoxia condition and the influence of hypoxia to biosynthesis of m iR N A , w hich m ay provide som e new ideas to the research of m iR N A on determ ining the cause of m echanical asphyxia death in the field of forensic m edicine.