Role of autophagy in renal disease
10.3760/cma.j.issn.2095-428X.2017.05.022
- VernacularTitle:自噬在肾脏疾病中的作用
- Author:
Xu SONG
;
Hongzhu LU
- Keywords:
Autophagy;
Autophosome;
Kidney disease
- From:
Chinese Journal of Applied Clinical Pediatrics
2017;32(5):398-400
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is the cell biology process in which cytoplasmic components are degraded in lysosomes to maintain cellular homeostasis,it is involved in the pathophysiology of several kidney diseases (podocytopathies,IgA nephropathy,diabetic nephropathy,hereditary kidney disease),but its specific effect is still controversial.Most studies suggest that autophagy plays a protective role in kidney diseases,in the future,it may become a new target for the prevention and treatment of kidney disease.
