Red blood cell casts induced acute renal failure in IgA nephropathy: a childhood case report with literature review
10.3969/j.issn.1000-3606.2017.02.009
- VernacularTitle:红细胞管型堵塞致急性肾衰竭IgA肾病1例报告并文献复习
- Author:
Hongwen ZHANG
;
Jieyuan CUI
;
Baige SU
;
Yong YAO
- Keywords:
childhood;
IgA nephropathy;
red blood cell casts;
acute renal failure
- From:
Journal of Clinical Pediatrics
2017;35(2):115-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the rare cause of renal failure in childhood IgA nephropathy.MethodsA six year-old boy presented with recurrent gross hematuria for 3 months and increased serum creatinine for 5 days, blood and urine routine test, renal function, urinary protein concentration and renal biopsy were performed for diagnosis.Results The boy had three episodes of recurrent gross hematuria with a predisposed respiratory tract infection, he recovered within a week after antibiotic therapy from previous two episodes, but oliguria and renal failure were occurred in the third episode. Renal biopsy showed IgA nephropathy with presence of red blood cell casts in as much as 50% of the tubular lumen and acute tubular lesion. His renal function recovered gradually to normal within 4 weeks after treatment with anti-infection, diuresis and alkalization of urine. Conclusions This article reported the renal failure case induced by tubular damage and obstruction by red blood cell casts in childhood IgA nephropathy.
