Progress on roles of type 2 innate lymphoid cells in the pathogenesis of asthma
10.3969/j.issn.1000-3606.2017.02.017
- VernacularTitle:ILC2参与哮喘发病机制的研究进展
- Author:
Qin JIANG
- Keywords:
type 2 innate lymphocyte cells;
asthma;
pathogenesis
- From:
Journal of Clinical Pediatrics
2017;35(2):148-152
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 innate lymphoid cell (ILC2) is a new member of the innate lymphoid cell family discovered recently. After being exposed to antigens, ILC2 was activated by epithelial cell-derived cytokines, lipid mediators and TNF family member TL1A to promote structural and immune cell responses in the airways. These cells are critical components of the innate immune response involved in the pathogenesis of asthma. This paper summarizes the progress on the roles of type 2 innate lymphoid cells in the pathogenesis of asthma.
