Clinical efficacy of fluticasone propionate combined with noninvasive positive pressure ventilation on COPD and its effect on pulmonary function
10.3969/j.issn.1005-1678.2017.02.081
- VernacularTitle:丙酸氟替卡松联合无创正压通气治疗COPD的临床疗效及对患者肺功能的影响
- Author:
Tingxia FU
;
Hongxing ZHENG
;
Jianjiang ZHANG
- Keywords:
fluticasone propionate;
noninvasive positive pressure ventilation;
combine;
COPD;
disease recurrence rate
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(2):261-263
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of fluticasone propionate combined with noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease (COPD).Methods 88 cases of COPD patients from October 2014 to October 2016 in our hospital were selected and randomly divided into two groups of the control group observation group with 44 cases in each group.The control group was treated with conventional treatment, the observation group was treated with fluticasone propionate plus noninvasive positive pressure ventilation, and then the curative effect of the two groups was compared.Results The total effective rate of observation group was 100% higher than that of the control group 70.5%, the difference was statistically significant (P<0.05), after treatment, the observation group of FVC (2.50 +0.32) L, FEV1 (1.36 +0.20) L, FEV1%(51.23+4.32), PaO2(10.51+2.10) kPa, PaCO2(5.15 +1.19) kPa, compared with the control group, the difference was statistically significant (P<0.05), the observation group recurrence rate 4.5% was lower than the control group 13.6%, the difference was statistically significant (P <0.05).Conclusion COPD patients with fluticasone propionate combined noninvasive positive pressure ventilation, can effectively improve lung function, reduce disease recurrence rate, a significant effect.
