Comparison of effects of laparoscopic operation and open operation for the peripheral blood T lymphocyte subsets and Th1 Th2 of patients with severe acute pancreatitis
10.3969/j.issn.1005-1678.2017.02.096
- VernacularTitle:腹腔镜手术与开腹手术对重症急性胰腺炎患者外周血T淋巴细胞亚群及Th1Th2的影响比较
- Author:
Haixing SHEN
;
Yafeng WAN
;
Qijun YANG
- Keywords:
laparoscopic operation;
open operation;
severe acute pancreatitis;
peripheral blood T lymphocyte subsets;
Th1Th2
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(2):305-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the influence degree of laparoscopic operation and open operation on peripheral blood T lymphocyte subsets and Th1Th2 in patients with severe acute pancreatitis.Methods 54 patients who underwent surgical treatment in our hospital from February 2013 to December 2014 were selected as the subjects, 27 patients with severe acute pancreatitis who were treated with open operation as group A , 27 cases who were treated with laparoscopic operation at the same time were selected as group B , and then the peripheral blood T lymphocyte subsets and serum Th1Th2 indexes of two groups before the operation and at first,third and seventh day after the operation were respectively detected, then the detection results of two groups were compared.Results The peripheral blood T lymphocyte subsets and serum Th1Th2 indexes of group B at first, third and seventh day after the operation were all significantly better than those of group A , the difference was statistically significant ( P<0.05 ) , and the detection results of group A and group B at third day after the operation were worse than those at other time , the difference was statistically significant (P<0.05).Conclusion The influence of laparoscopic operation and open operation on T lymphocyte subsets and Th1Th2 in peripheral blood of patients with severe acute pancreatitis, the adverse effects of laparoscopic operation on the above indicators were relatively small.