Application of Fufang Xueshuantong capsule in patients with optic atrophy of glaucoma and its influence on ocular hemodynamics
10.3969/j.issn.1005-1678.2017.02.023
- VernacularTitle:复方血栓通胶囊治疗青光眼视神经萎缩患者的效果及对眼血流动力学的影响
- Author:
Yi WANG
;
Yongbao CAO
;
Jiehui XU
;
Ren LI
- Keywords:
compound Xueshuantong capsule;
glaucoma;
optic atrophy patients;
ocular hemodynamics
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(2):78-80
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of Fufang Xueshuantong capsule on glaucomatous optic atrophy and its influence on ocular hemodynamics.Methods 124 cases of patients with glaucomatous optic atrophy from April 2014 to December 2016 in our hospital were selected,and randomly divided into experimental group and control group according to the order of hospital admission , with 62 cases in each group.The control group was treated with nerve growth factor plus vitamin needling,the experimental group was treated with nerve growth factor and vitamin and compound Xueshuantong capsule.Observation and comparison the total effective rate, visual function (visual acuity, total gray value) improvement of the two groups of patients, as well as the changes of ocular hemodynamic parameters (systolic peak velocity, diastolic End-stage blood flow velocity, resistance index, pulsatility index).Results The total effective rate of the experimental group was 93.55%(58/62), the total effective rate of the control group was 70.97%(44/62), the total effective rate of the experimental group was higher than the control group (P <0.05)).After treatment, the visual acuity of the experimental group was significantly higher than the control group, the total gray value of the experimental group was significantly lower than the control group (P<0.05).The peak systolic velocity and end diastolic velocity in the experimental group were significantly higher than those in the control group (P<0.05).The resistance index and pulsatility index in the experimental group were lower than those in the control group (P<0.05). Conclusion Compound Xueshuantong capsule is effective in the treatment of glaucomatous optic atrophy , can improve the ocular hemodynamics and improve the visual function.
