Effects of astragalus injection auxiliary on the levels of Serum troponin I and related inflammatory factors inpatients with infantile viral myocarditis
10.3969/j.issn.1005-1678.2017.02.034
- VernacularTitle:黄芪注射液对小儿病毒性心肌炎患儿血肌钙蛋白Ⅰ及相关炎性因子水平的影响
- Author:
Shuijing FANG
;
Huihua ZHANG
;
Jianwu CHE
- Keywords:
astragalusinjection;
viralmyocarditis;
serumtroponin Ⅰ;
creatine kinase isoenzyme;
creatine kinase;
IL-4;
IL-6;
IL-23
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(2):113-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of astragalus injection auxiliary on the levels of serum troponin I ( cTn I ) , creatine kinase isoenzyme(CK-MB), creatine kinase(CK), interleukin 4(IL-4), interleukin 6(IL-6) and interleukin 23(IL-23) in patients with infantile viral myocarditis.Methods 70 patients with infantile viral myocarditis who were treated in Zhejiang Quzhou Hospital were selected and randomly divided into control group andexperiment group,with35 cases in each group.Patients in control group were treated with 1, 6 -two-diphosphate fructose, a lot of vitamin C and polarized liquid conventional treatments, patients in experiment group were treated withastragalus injectionon the base of control group.After treatment with two weeks, the serum cTn I, CK-MB, CK,IL-4,IL-6 andIL-23 levels of two groups were compared, and the clinical total effective rate were observed.Results Compared with pre-treatment, the serum cTn I, CK-MB, CK, IL-6 and IL-23 levels of the two groups were decreased, the IL-4 level increased(P<0.05).ompared with the control group, the serum cTn I, CK-MB, CK, IL-6and IL-23 levels of experiment group were lower, theIL-4 levelwashigher ( P <0.05 ) . The clinical total effective rate of experiment group was higher than control group ( P <0.05 ) . Conclusion Astragalus injectioncombined with conventional therapy aremore effective in treatment with infantile viral myocarditis .
