The recent progress of bone coupling mechanism:function of bone marrow derived factors
10.3760/cma.j.issn.1000-6699.2017.02.015
- VernacularTitle:骨转换耦联机制新进展-骨髓局部因子的作用
- Author:
Feng XU
;
Lingqing YUAN
- Keywords:
Bone Remodeling;
Bone coupling;
Cytokines;
membrane molecules
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(2):156-158
- CountryChina
- Language:Chinese
-
Abstract:
Bone remodeling is an ordered process of coupling of bone resorption and bone formation. Cytokines secreted by different bone cells and membrane molecules expressed by bone cells are involved in regulation of coupling of bone resorption and bone formation. To reveal the mechanism of bone coupling is of great significance in the study and diagnosis of osteoporosis and other metabolic bone diseases. In the present review, we summarize the progression of mechanisms by which cytokines and the related membrane molecules are regulating the coupling of bone resorption and bone formation.