Long no-coding RNAs and prostate cancer
10.16571/j.cnki.1008-8199.2017.02.020
- VernacularTitle:长链非编码RNA在前列腺癌中的作用及研究进展
- Author:
Yitian GUO
;
Bin XU
- Keywords:
Prostate Cancer;
LncRNAs;
Gene Regulation;
Therapeutic targets
- From:
Journal of Medical Postgraduates
2017;30(2):199-203
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs ( lncRNAs) are a class of RNA molecules which are unable to codify proteins. They express abnormally in tumor cells including prostate cancer cells and play a significant role in development of tumor. Some lncRNAs have been proven to affect physiological processes of prostate cells and act as tumor suppressor or activator and could be regulated through several methods. Thus, lncRNAs have the potential to be therapeutic targets of prostate cancer. This review introduces expressed abnormally ln-cRNAs in prostate cancer and their functions and mechanisms in prostate cancer.
