Endothelial dysfunction and cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2016.12.011
- VernacularTitle:内皮功能障碍与脑小血管病
- Author:
Xuemei CHEN
- Keywords:
Cerebral Small Vessel Diseases;
Endothelium;
Vascular;
Blood-Brain Barrier;
Inflammation;
Biomarkers
- From:
International Journal of Cerebrovascular Diseases
2016;24(12):1111-1114
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral smal vessel disease (CSVD) refers to various diseases of brain perforating arterioles, capilaries and venules caused syndrome of clinical, cognitive and pathological manifestation. It is not only the main cause of stroke, but also causes cognitive impairment and dementia. Its pathogenesis is not fuly understood. Many studies have confirmed that endothelial dysfunction plays an important role in the pathogenesis of CSVD. This article review s the relationship between endothelial dysfunction and CSVD in order to provide new ideas for etiology, pathogenesis, and clinical prevention and treatment of CSVD.
