Toll-like receptor 2 and ischemic cerebral white matter lesion
10.3760/cma.j.issn.1673-4165.2016.12.014
- VernacularTitle:Toll样受体2与缺血性脑白质损害
- Author:
Shuang LI
;
Fuqiang GUO
- Keywords:
Brain Ischemia;
Toll -Like Receptor 2;
Oligodendroglia;
Leukoencephalopathies;
Demyelinating Diseases
- From:
International Journal of Cerebrovascular Diseases
2016;24(12):1125-1128
- CountryChina
- Language:Chinese
-
Abstract:
Toll-like receptor 2 (TLR2) is the most w idely expressed receptor in the Toll-like receptor family, and is also an important pattern recognition receptor of the innate immune system to pathogenic microorganisms. In addition, TLR2 can also identify endogenous risk signals and participate in non -pathogenic microbial inflammatory reaction in ischemic injury. The role of TLR2 and its signal transduction in ischemic cerebral w hite matter lesions have received more and more attention. This article reviews the relationship between TLR2 and ischemic cerebral white matter lesion.
