A Case of Amelanotic Melanoma Developing in a Burn Scar.
- Author:
Hong Jin PARK
;
Dong Won LEE
;
Sung Woo CHOI
;
Baik Kee CHO
;
Moon Jae CHO
;
Sang In SHIM
- Publication Type:Case Report
- Keywords:
Burn Scar;
Marjolins Ulcer;
Amelanotic Melanoma
- MeSH:
Biopsy;
Burns*;
Carcinoma, Basal Cell;
Cicatrix*;
Female;
Follow-Up Studies;
Heel;
Humans;
Melanins;
Melanoma, Amelanotic*;
Middle Aged;
Mycobacterium bovis;
Neoplasm Metastasis;
Recurrence;
S100 Proteins;
Skin;
Skin Neoplasms;
Transplants
- From:Korean Journal of Dermatology
1995;33(2):339-343
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinomatous degeneration of chronic scars, known as Marjcinulcer, are relatively rare. The majority of them are quamous cell carcinoma or other skin cancers including basal cell carcinoma. But malignant melanone, especially amelanotic melanoma oveloping from a chronic burn scar is extremely rare. We have experiencedl a case of amelanotic melanoma arising ron a chronic burn scar in a patient, 53 year-old female, who had a painful erythematous ulcra edonodule on the left heel for about 20 years since she had sustained a burn there at the age of 1 year. Although there are no melanin pigments in hematoxylinsin(H & E) stain as well a Fontana Masson stain, a biopsy specimen from the skin lesion revealed cytologic atypia and junctional activity in the dermoepidermal junction arcl positive immunohistochemical staier, for S-100 protein, which is consistent with amelanotic melanoma. lesion was widely excised and a skin graft was dure She was also treated with intralesional BCG injection and recurrence or metastasis was ot detected during the follow up period of 6 months.
