Clinical study on Jianpi-Gushen decoction combined with vitamin E and human chorionic gonadotropin for the patients with threatened abortion in early pregnancy
10.3760/cma.j.issn.1673-4246.2017.03.007
- VernacularTitle:健脾固肾方联合维生素E和人绒毛膜促性腺激素治疗妊娠早期先兆流产临床研究
- Author:
Shuli LI
;
Aiping LI
;
Fengxin XIAO
;
Dunxin ZHANG
- Keywords:
Abortion;
threatened;
Progesterone;
Human chorionic gonadotropin;
beta subunit;
human;
Jianpi-Gushen decoction
- From:
International Journal of Traditional Chinese Medicine
2017;39(3):215-217
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of Jianpi-Gushen decoction combined with vitamin E and human chorionic gonadotropin for the patients with threatened abortion in early pregnancy. Methods A total of 154 patients with threatened abortion who met the inclusion criteria were divided into two groups by a random digital table, with 77 patients in each. The control group was treated with intramuscular injection of human chorionic gonadotropin (HCG) combined with vitamin E, while the observation group was treated with Jianpi-Gushen decoction based on the treatment of control group. The levels of serum β-HCG were detected by radioimmunoassay before and after treatment, and the levels of progesterone were detected by electrochemiluminescence assay, and the efficacy was evaluated. Results The total effective rate in the observation group was 90.9% (70/77), and control group was 77.9% (60/77). The difference between two groups was significantly different (χ2=4.936, P=0.026). The serum β-HCG level (22383.41 ± 4387.67 mIU/ml vs. 15728.66 ± 3375.93 mIU/ml, t=5.614) and progesterone level (58.53 ± 18.77 nmol/L vs. 43.45 ± 17.46 nmol/L, t=2.674) in the observation group after treatment were higher than those in the control group (P<0.01). Conclusions The Jianpi-Gushen decoction combined with vitamin E and HCG could increase the levels of serum β-HCG and progesterone and improve the clinical effect.
