Detection of Brain Neurotransmitters in Patients with Vasovagal Syncope with Encephalofluctuogram Technology

VernacularTitle:脑电超慢涨落图分析血管迷走性晕厥患者脑内神经递质功能的变化
Author: Jun XIAO ; Lin WANG ; Chaoying ZHU ; Hongmei LI ; Lun SHU ; Hongling XU ; Yusong GUO ; Chao HU ; Junxian XUE ; Xin CHEN
Keywords: vasovagal syncope; neurotransmitter; encephalofluctuogram technology
From: Chinese Journal of Rehabilitation Theory and Practice 2017;23(3):349-351
CountryChina
Language:Chinese
Abstract: Objective To observe the changes of brain neurotransmitters in patients with vasovagal syncope (VVS) with encephalofluc-tuogram technology (ET). Methods From August, 2015 to December, 2016, 30 patients with VVS were selected as case group, 30 controls matched with sex and age were selected from the outpatients without syncope. They were detected the function of gamma aminobutyric acid (GABA), glutamate (Glu), 5-hydroxytryptamine (5-HT), acetylcholine (Ach), norepinephrine (NE) and dopamine (DA) with ET. Results There was no significant difference between the two groups in the values of GABA, Glu, 5-HT, Ach and DA (t<1.680, P>0.05), while the values of NE was higher in the case group than in the control group (t=-3.552, P<0.001). Conclusion VVS may be related to the high level of activity of NE in the brain.