Nursing experience of children with neuroblastoma developing adverse reaction after re-transfusion of chimeric antigen receptor-transduced T-cells
10.3761/j.issn.0254-1769.2017.03.011
- VernacularTitle:神经母细胞瘤患儿接受嵌合抗原受体修饰T细胞回输后不良反应的护理
- Author:
Yaguang DING
;
Wen ZHAO
;
Xinyi WU
;
Xiaoli MA
- Keywords:
Child;
Neuroblastoma;
Chimeric Antigen Receptor-transduced T Cell;
Nursing Care
- From:
Chinese Journal of Nursing
2017;52(3):307-310
- CountryChina
- Language:Chinese
-
Abstract:
This paper summarized nursing experience of 11 patients with refractory or relapsed neuroblastoma who developed CAR-T adverse reaction after receiving the transfusion.Nursing key points included:close monitoring of changes of vital signs,especially body temperature and blood pressure;observation of changes of skin,avoiding scratching when skin rash occurred,and daub calamine lotion was applied;strict recording input and output volume of 24 hours,ensuring patency of venous catheters and constant infusion of liquid,observing changes of urine volume and color;strengthening prevention of infection,strict operation of antiseptic technique,protective isolation when moving in laminar flow clean room;monitoring changes of face,breathing,blood oxygen and so on.Through careful treatment and nursing care,the treatment of children was ensured.
