ABO-incompatible adult living donor liver transplantation: a retrospective analysis
10.3760/cma.j.issn.1007-8118.2017.03.003
- VernacularTitle:成人活体ABO血型不合肝移植的回顾性分析
- Author:
Weiwei WANG
;
Huanzhou XUE
;
Jianjun SUN
;
Sidong WEI
;
Huibo ZHAO
;
Zhantao XIE
;
Gaofeng TANG
;
Huaen XU
;
Jianbin CHEN
;
Guoyong CHEN
- Keywords:
Living donor liver transplantation;
ABO-incompatible;
Plasmapheresis;
Prognosis
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(3):154-157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical efficacy and outcomes of adult patients who underwent ABO-incompatible living donor liver transplantation.Methods The clinical data of 7 patients who underwent ABO-incompatible living donor liver transplantation at the Henan Provincial People's Hospital and Zhengzhou People's Hospital from January 2013 to December 2015 were analyzed retrospectively.Age,gender,primary disease,blood type antibody level,graft volume/standard liver volume (GV/SLV),postoperative complications and prognosis were analyzed.Results The recipients' average GV/SLV was 52.0％.There were 4 recipients who underwent splenectomy,including 3 patients who underwent the procedure concurrently,and one patient who underwent the procedure a few years before,the liver transplantation.Seven recipients were treated with plasmapheresis,Rituximab and Basiliximab.No patients experienced acute rejection during the perioperative period,and the 1-year survival rate was 85.7％ (6/7).Conclusion ABOincompatible liver transplantation in adult living donor can have favorable clinical outcomes using appropriate preoperative evaluation for recipients,optimized surgical procedures,pretransplant plasmapheresis,and perioperative Rituximab,Basiliximab injection and intravenous immunoglobulin administration.
