Progress in the relevance of long non-coding RNA and bronchial asthma
10.3760/cma.j.issn.1673-4408.2017.03.004
- VernacularTitle:长链非编码RNA与支气管哮喘的相关性研究进展
- Author:
Qian WANG
- Keywords:
Long non-coding RNA;
Asthma
- From:
International Journal of Pediatrics
2017;44(3):161-164
- CountryChina
- Language:Chinese
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Abstract:
Long non-coding RNAs (lncRNA) are a class of non-coding RNAs (ncRNA) that contain over 200 nucleotides.Asthma is one of the most common diseases in children and the main characteristics including airway inflammation,airway hyperresponsiveness and airway remodeling.Studies have shown that some lncRNAs participate in the identification of steroid-resistant asthma and have an important role in the treatment of glucocorticoid hormone,while some lncRNAs have a link with microRNAs (miRNA),inflammation,epigenetic modification and airway smooth muscle cells,lncRNAs maybe closely related to the development of asthma.This review will discuss the association between lncRNAs and asthma.
