Curative efficacy of Xianlinggubao capsules combined with Lugua polypeptide injection in vertebral osteoporosis
10.3969/j.issn.1005-1678.2017.03.044
- VernacularTitle:仙灵骨葆胶囊联合鹿瓜多肽注射液对椎体骨质疏松的临床疗效
- Author:
Yongxin JIN
;
Xiaoqiang LV
;
Zhiying LIU
- Keywords:
Xianlinggubao capsules;
Lugua polypeptide injection;
vertebral osteoporosis;
clinical effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):147-149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore curative efficacy of Xianlinggubao capsules combined with Lugua polypeptide injection in treatment of vertebral osteoporosis.Methods 90 patients of vertebral osteoporosis from March 2014 to March 2015 in our haspital were selected as research objects and randomly divided into the observation group and control group,with 45 cases in each group.The control group were treated with Lugua polypeptide injection, while the observation group were treated with Xianlinggubao capsules combined with Lugua polypeptide injection.Then bone mineral density, osteocalcin, visual analogue scale (VAS), Oswestry disability index (ODI) score, curative effect in two groups after treatment were compared.Results Ater treatment, bone mineral density, osteocalcin in observation group was than that in control group [(0.99 ±0.13)g/cm2 vs(0.89 ±0.14)g/cm2, (41.05 ±5.30)μg/L vs(35.80 ±5.23)μg/L],the difference was statistically significant(P<0.05); VAS、ODI score in observation group were lower than those in control group[(1.21 ±0.30)分vs(4.65 ±1.08)分、(18.24 ±4.97)% vs(31.26 ±5.73)%],the difference was statistically significant (P<0.05).The total effective rate of observation group was statistically higher than that in the control group 95.55%(43/45),the difference was statistically significant vs77.77%( 35/45 ) ( P<0.05 ) .Conclusion Xianlinggubao capsules combined with Lugua polypeptide injection is well for vertebral osteoporosis,which can improve the bone metabolism of patients, promote bone growth and improve treatment efficacy.
