Influence of Shenmai injection for the postoperative infection and related serum indexes of patients with breast cancer
10.3969/j.issn.1005-1678.2017.03.046
- VernacularTitle:参麦注射液对乳腺癌患者术后感染及相关血清指标的影响
- Author:
Pengfei LI
;
Xiaochun WANG
;
Linbo ZHU
;
Pengbin ZHANG
;
Ji LI
- Keywords:
Shenmai injection;
breast cancer;
postoperative infection;
infection related serum indexes
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(3):153-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of Shenmai injection for the postoperative infection and related serum indexes of patients with breast cancer,in order to provide evidence for the prevention of patients'postoperative infection.Methods 90 patients with breast cancerwere selected as the study object,and all the patients were randomly divided into control group(conventional postoperative treatment group)45 cases and observation group (conventional treatment and Shenmai injection group)45 cases,then the postoperative infection rates,inflammatory indexes and immune indexes before the treatment and after the treatment at different time were compared .Results The total postoperative infection rate of observation group was one case (2.22%),and it had no obviously difference compared with four cases (8.89%) of control group,the inflammatory indexes including PCT, TNF-α, IL-6 and hs-CRP at first,third and seventh day after the treatment were all lower than those of control group ,the immune indexes including CD3 +、CD4 +、CD8 +及 CD3 +CD4 +were all better than those of control group ( all P<0.05 ) .Conclusion The Shenmai injection can effectively control the postoperative infection rate of patients with breast cancer,and it also plays active improvement role for the infection related indexes.