Research Advance in the Role of Toll-like Receptors in Hepatocarcinogenesis
- VernacularTitle:Toll样受体在肝癌中作用的研究进展
- Author:
Xing LIU
;
Yalian SA
- Keywords:
Toll-like receptors;
Toll-like receptors signaling pathway;
Hepatocellular carcinoma;
Tumor immunotherapy
- From:
Journal of Kunming Medical University
2016;37(7):121-125
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is the second largest cause of cancer deaths worldwide.TLRs signal transduction pathways are related to the progress of HCC.As an innate immune recognition receptors on the surface of the cell,TLRs are involved in the ligand-mediated activation of various cells and the secretion of cytokines in liver through signal transduction,which is part of the cause and development of HCC.A better understanding of TLRs and these signaling pathways in the liver will help us understand the mechanism of hepatocarcinogenesis and provide a new therapeutic target for HCC.
