A review of the effect of T-2 toxin on chondrocytes cultured in vitro
10.3760/cma.j.issn.2095-4255.2017.02.021
- VernacularTitle:T-2毒素对体外培养细胞影响的研究概况
- Author:
Haijuan REN
;
Tiantian LI
;
Xiong LING
;
Yanhong CAO
- Keywords:
T-2 toxin;
Chondrocytes;
In vitro
- From:
Chinese Journal of Endemiology
2017;36(2):152-156
- CountryChina
- Language:Chinese
-
Abstract:
T-2 toxin is a secondary fungal metabolite that belongs to the trichothecene mycotoxin family.T-2 toxin can lead to the structural and functional changes of cartilage cells and cartilage cell degeneration and necrosis.With strong cytotoxicity,T-2 toxin can cause definite damage to cartilage cells.In this paper,we reviewed recent studies on the effects of T-2 toxin on chondrocyte apoptosis,ultra structural changes and extracellular matrix in vitro.
