Evaluating endothelial function of the dorsal artery of foot in patients with type 2 diabetes by ultrasound combined with warm bath test
10.3760/cma.j.issn.1004-4477.2017.02.017
- VernacularTitle:超声结合温浴试验评价2型糖尿病患者足背动脉内皮功能
- Author:
Xiuyun LI
;
Qianqian CHEN
;
Yan JIAO
;
Jinjue ZHENG
;
Yan YANG
;
Yaping ZHAO
;
Chao ZHENG
;
Chunpeng ZOU
- Keywords:
Ultrasonography;
Arteria dorsalis pedis;
Vascular endothelial function;
Diabetes mellitus;
type 2;
Warm bath test
- From:
Chinese Journal of Ultrasonography
2017;26(2):155-158
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of endothelial function of dorsal artery of foot in patients with type 2 diabetes(T2DM) by high frequency ultrasound combined with warm bath test.MethodsThirty-five patients with T2DM and thirty normal people were collected,all subjects were examined by high frequency ultrasound.Diameter of brachial artery in baseline and after reactive hyperaemia were detected;Diameter of dorsal artery of foot in baseline and after the foot immersed in 40℃ warm water for 5 minutes were acquired.Flow mediated dilatation of dorsalis pedis artery(FMDDPA) and flow mediated dilatation of brachial artery(FMDBA) were calculated and compared.Multiple stepwise regression analysis was used to examine the correlation between FMDDPA and hemoglobin A1c(HbAlc). Results The FMDDPA and FMDBA were decreased in patients with T2DM (P<0.01).The FMDDPA and FMDBA were correlated significantly(r=0.864,P<0.01).In stepwise regression analysis,HbA1c is the most affecting factor for FMDDPA (R2=0.321,P<0.01).Conclusions Ultrasound combined with warm bath test can be used to detect the change of endothelial function of dorsal artery of foot in patients with T2DM,which have a certain clinical application value in endothelial function of terminal limb artery.
