Research progress on exosome-derived non-coding RNA in digestive system malignancy
10.19401/j.cnki.1007-3639.2017.04.010
- VernacularTitle:外泌体源性非编码RNA在消化系统恶性肿瘤中的研究进展及展望
- Author:
Shulin YU
- Keywords:
Exosome;
Non-coding RNAs;
Digestive system malignancy
- From:
China Oncology
2017;27(4):297-303
- CountryChina
- Language:Chinese
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Abstract:
Exosome is a kind of biological membrane structure at nanometer level. It is secreted by various cells and widely distributed in most body fluids. Biological active substances, including non-coding RNAs and proteins, have been identified in the exosomes. Exosome may be involved in cell-to-cell substance transporting and signaling. Non-coding RNAs have important function of regulating gene expression and also play key roles in the occurrence and development of many cancers. Research on exosome-derived non-coding RNA is a new hotspot at present. In this paper, we will review research progress on exosome and exosome-derived non-coding RNA in digestive system malignancy.
