Research progress of DNA methylation in thyroid cancer
10.19401/j.cnki.1007-3639.2017.04.011
- VernacularTitle:甲状腺癌的DNA甲基化研究进展
- Author:
Yiming CAO
- Keywords:
Thyroid cancer;
Epigenetics;
DNA methylation
- From:
China Oncology
2017;27(4):304-311
- CountryChina
- Language:Chinese
-
Abstract:
DNA methylation is an important epigenetic modification. Evaluating the status of DNA methylation could be useful for diagnosis, prognostic evaluation and predicting the risk of cancer. Thyroid cancer is the most prevalent endocrine malignancy in humans. Growing evidence shows that epigenetic abnormalities participate with genetic alterations in carcinogenesis of thyroid cancer. This article reviewed the recent research progress of DNA methylation in thyroid cancer.
