Impact of Body Mass Index on Long-term Prognosis in Patients of Acute ST-segment Elevation Myocardial Infarction After Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2017.04.010
- VernacularTitle:体重指数对行介入治疗的急性ST段抬高型心肌梗死患者长期预后的影响
- Author:
Huanhuan WANG
;
Xueyan ZHAO
;
Zhan GAO
;
Shubin QIAO
;
Yuejin YANG
;
Runlin GAO
;
Bo XU
;
Jinqing YUAN
- Keywords:
Body mass index;
Myocardial infarction;
Angioplasty;
transluminal;
percutaneous coronary
- From:
Chinese Circulation Journal
2017;32(4):348-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the impact of body mass index (BMI) on long-term prognosis in patients of acute ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). Methods: A total of 1435 consecutive STEMI patients received PCI in our hospital from 2013-01 to 2013-12 were enrolled. Based BMI (kg/m2), the patients were divided into 3 groups: Normal weight group, the patients with 18.5≤BMI<24.0, n=365, Overweight group, 24.0≤BMI<28.0, n=718 and Obese group, BMI≥28.0, n=352. The impact of BMI on major adverse cardiovascular and cerebral events (MACCE) was observed; weather BMI had predictive value for all-cause mortality and cardiac death was analyzed. Results: All-cause mortality in Obese group was lower than Normal weight group (0.6% vs 3.0%), P=0.027; while the incidences of bleeding, stroke, in-stent thrombosis, blood revascularization, re-myocardial infarction and cardiac death were similar among 3 groups. Multivariate analysis revealed that obesity was an independent predictor for all-cause death (HR=0.201, 95% CI 0.043-0.943, P=0.042), BMI was not the independent predictor for cardiac death. Conclusion: For STEMI patients after PCI treatment, the individuals with obesity had the better prognosis than those with normal weight and overweight. Obesity was an independent predictor for all-cause death and obesity paradox was applicable in such population.
