Drug resistance and nosocomial infection analysis of 1521 strains MDR
10.3760/cma.j.issn.1008-1372.2017.03.022
- VernacularTitle:1521株多重耐药菌的耐药情况及院内感染分析
- Author:
Xiaobo TIAN
;
Shujuan PAN
;
Gui ZHANG
;
Yu LIU
;
Baokun DONG
- Keywords:
Drug resistance,bacterial;
Bacteria/DE;
Cross infection;
Microbial sensitivity tests;
Spectrometry,mass,matrix-assisted laser desorption-ionization
- From:
Journal of Chinese Physician
2017;19(3):403-406
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the situation of drug resistance and nosocomial infection of multi-drug resistant bacteria (MDR),guidance for clinical rational use of antibiotics.Methods A total of 1521 strains of MDR was isolated from January 2015 to December in Beijing Tongren Hospital,using matrixassisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) identification of bacteria,VITEK-2 Compact and Kirby Bauer (KB) method for drug sensitivity test.Results In 1 521 strains of MDR,Acinetobacter Baumanii were 589 strains (38.7％),nosocomial infection rate were 16.6％;350 strains of Escherichia coli (23.0％),nosocomial infection rate were 9.0％;249 strains of Staphylococcus aureus (16.4％),nosocomial infection rate were 2.7％;171 strains of Klebsiella pneumoniae (11.2％),nosocomial infection rate were 14.3％;150 strains of pseudomonas aeruginosa (9.9％),nosocomial infection rate were 64.7％;12 strains of Enterococcus faecium (0.8％),nosocomial infection rate were 16.7％.MDR Acinetobacter Baumanii,MDR Pseudomonas aeruginosa,extended-spectrumβ-lactamase (ESBL) + Escherichia coli and ESBL + Klebsiella pneumoniae resistance rate to Imipenem were 100％,91.5％,0.6％ and 55.6％.Conclusions MDR pseudomonas aeruginosa (MDR-PAE),MDR acinetobacter baumanii (MDR-AB) and ESBL + Klebsiella pneumoniae were highly resistant,and the nosocomial infection rate were higher.
