Comparsion of pathological differences between cervical high-grade intraepithelial lesions positive resection surgical margin after cold knife conization and hysterectomy

VernacularTitle:子宫颈高级别上皮内病变冷刀锥切术后切缘阳性和全子宫切除术后病理结果比较
Author: Yan QIN ; Jie TIAN ; Xiaoyan LIU ; Ying CHEN ; Juhua FAN ; Kaixian DENG
Keywords: cervical neoplasm; high-grade intraepithelial lesions; cold knife conization; hysterectomy
From: Chinese Journal of Clinical and Experimental Pathology 2017;33(1):35-37
CountryChina
Language:Chinese
Abstract: Purpose To compare the pathological differences between cervical high-grade intraepithelial lesions (CHGIL) positive resection surgical margin after cold knife conization and total hysterectomy,and to explore how to take further clinical treatment measures.Methods The pathologic results of 74 patients with CHGIL positive surgical margin after cold knife conization and hysterectomy were analyzed retrospectively.Results There was a correlation between positive cervical incision margin and residual uterine lesion (P ＜ 0.01).Age,menopause status,gland involvement did not related to residual uterine lesions(P ＞ 0.05).There was significant correlation between the lesion-related quadrant and the residual rate of uterine lesion (P ＜ 0.01).Conclusion Cold knife conization and hysterectomy are safe and effective treatments for CHGIL.However,for the positive resection surgical margin after cold knife conization cases,hysterectomy should be carefully chosen and may choose conservative treatment or re-cone cutting.