Adipose tissue macrophages: New target for immunotherapy of obesity?
10.3760/cma.j.issn.1000-6699.2017.03.012
- VernacularTitle:脂肪组织巨噬细胞:免疫治疗肥胖的新靶点?
- Author:
Bingwen LIU
;
Yufei XIANG
;
Zhiguang ZHOU
- Keywords:
Macrophage;
Chronic inflammation;
Obesity;
Insulin resistance
- From:
Chinese Journal of Endocrinology and Metabolism
2017;33(3):236-241
- CountryChina
- Language:Chinese
-
Abstract:
Intensive attention has been drawn to macrophages in obesity after the discovery of macrophage infiltration in adipose tissue. This review updates of adipose tissue macrophages in the immune-pathophysiology of obesity, including new progression on the adipose tissue macrophages phenotype and the potential of beige fat induction by M2 macrophage, which inspires a novel therapy for obesity and insulin resistance.
