Hair cortisol concentration measurement in researches on stress-related diseases
10.3969/j.issn.1000-6729.2017.02.003
- VernacularTitle:头发皮质醇浓度测定在应激相关疾病研究中的应用
- Author:
Quan ZHANG
;
Huihua DENG
- Keywords:
hair cortisol concentration;
hypothalamic-pituitary-adrenocortical axis;
long-term cortisol basal level;
stress-related diseases
- From:
Chinese Mental Health Journal
2017;31(2):108-114
- CountryChina
- Language:Chinese
-
Abstract:
Stress-related diseases are closely related to an abnormal cortisol secretion.Recent research implied that hair cortisol concentration which retrospectively records long-term cortisol basal level might possess superiority in the diagnosis of stresS-related diseases.This paper reviewed recent progresses in application of hair cortisol concentration in stress-related diseases (metabolic syndrome,obesity,cardiovascular disease,depression,PTSD,etc.) which showed abnormal long-term cortisol secretion in a wide range of situationS.This review proposed that the future research needs to take into accounts exclusion and/or balance of the influence factors,a longitudinal design in combination with acute-stress and chronic-stress biomarkers,and to develop new bio-markers related to hair cortisol concentration for study of stress related diseases,and establishment of standard protocols and clinical standards.
