The ingredients in Saengshik, a formulated health food, inhibited the activity of alpha-amylase and alpha-glucosidase as anti-diabetic function.
- Author:
Misook KIM
1
;
Eunji KIM
;
Han Sub KWAK
;
Yoonhwa JEONG
Author Information
- Publication Type:Brief Communication
- Keywords: Saengshik; alpha-amylase inhibition; alpha-glucosidase inhibition; total phenolic compounds; antioxidant activity
- MeSH: Acarbose; alpha-Amylases*; alpha-Glucosidases*; Angelica; Brassica; Catechin; Edible Grain; Cucurbita; Daucus carota; Dietary Supplements; Ethanol; Fabaceae; Gallic Acid; Food, Organic*; Hordeum; Oenanthe; Phenol; Phenols; Raphanus; Sorghum; Vegetables
- From:Nutrition Research and Practice 2014;8(5):602-606
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/OBJECTIVES: We investigated total 26 ingredients of Saengshik which will be commercially produced as an anti-diabetic dietary supplement. SUBJECTS/METHODS: Thirteen vegetables, nine cereals, three legumes and one seed were extracted with aqueous ethanol for 2 h at 60degrees C, and evaluated for their inhibitory effects against alpha-amylase and alpha-glucosidase and for total phenolic and flavonoid contents. RESULTS: All ingredients inhibited alpha-amylase activity except cabbage. Strong inhibitory activity of alpha-amylase was observed in leek, black rice, angelica and barley compared with acarbose as a positive control. Stronger inhibition of alpha-glucosidase activity was found in small water dropwort, radish leaves, sorghum and cabbage than acarbose. All Saengshik ingredients suppressed alpha-glucosidase activity in the range of 0.3-60.5%. Most ingredients contained total phenols which were in the range of 1.2-229.4 mg gallic acid equivalent/g dried extract. But, total phenolic contents were not observed in carrot, pumpkin and radish. All ingredients contained flavonoid in the range of 11.6-380.7 mg catechin equivalent/g dried extract. CONCLUSIONS: Our results demonstrate that Saengshik containing these ingredients would be an effective dietary supplement for diabetes.
