Effect of arthroscopic arthroplasty on short-term efficacy and stress factors in patients with primary primary osteoarthritis of the elbow
10.3760/cma.j.issn.1008-6315.2017.04.009
- VernacularTitle:关节镜下关节成形术对中期原发性肘关节骨关节炎患者的近期疗效及应激因子的影响
- Author:
Jing CHEN
;
Farui SUN
- Keywords:
Arthroscopic arthroplasty;
Primary osteoarthritis of the elbow;
Tumor necrosis factor α;
Interleukin 6;
Interleukin 10;
Adrenocorticotrophic hormone;
Stress factor
- From:
Clinical Medicine of China
2017;33(4):327-330
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of arthroscopic arthroplasty on the short-term efficacy and stress factors in patients with primary osteoarthritis of the elbow and to guide the clinical application.Methods From February 2013 to February 2016,32 patients with primary primary osteoarthritis of the elbow underwent arthroscopic arthroplasty in Xiaogan Hospital Affiliated to Wuhan University of Science and Technology.The levels of serum TNF-α,IL-6,IL-10,adrenocorticotrophic hormone(ACTH) and other stress factors were measured before and after the operation.The ROM,MEPS and VAS were used to evaluate the curative effect before,3 months and 6 months after operation.Results All patients were followed up successfully.The excellent rate was 96.9%(31/32) 1 year after the operation.Preoperative ROM,MEPS score,VAS score were (83.2±18.6) °,(63.2±14.5) points,(3.2±1.8) points;3 months,6 months postoperative ROM were (102.3±18.9) °,(124.3±15.4) °,and MEPS scores were (75.4±16.8) points and (89.5±14.3) points respectively,which were significantly higher than those before operation (ROM F value of 43.19,P<0.001;MEPS F value of 23.86,P<0.001).Three months,6 months postoperative VAS scores were (0.5±0.2) points and (0.3±0.1) points,which was significantly decreased(76.55,P<0.001);preoperative TNF-α,IL-6I,L-10,ACTH were respectively (12.5±2.5) μg/L,(5.4±2.3) ng/L,(10.5±4.0) ng/L,(22.4±6.3) ng/L,and were (38.4±8.6) μg/L,(25.6±8.4) ng/L,(23.1±4.8) μg/L,(58.6 ± 15.0) μg/L 1 day after surgery,which significantly increased compared with preoperative levels(P<0.05);1 week after patient TNF-α,IL-10 were respectively (9.4±1.2) μg/L,(7.5±3.5) ng/L,which decreased significantly(P<0.001).IL-6,ACTH were respectively (3.1±0.9) μg/L,(19.5±5.8) ng/L,which showed no significant difference(P>0.05).Conclusion For the modest primary osteoarthritis of the elbow,arthroscopy arthroplasty can achieve good therapeutic effect,improve the patient′s motor function and life quality,and minimally invasive surgical approach is conducive to relieve systemic stress.
