Desmoplastic fibroma of the bone: a clinicopathological analysis of seven cases
10.13315/j.cnki.cjcep.2017.02.008
- VernacularTitle:骨促结缔组织增生性纤维瘤7例临床病理分析
- Author:
Le XIE
;
Rongjun MAO
;
Kefei YANG
;
Jun LI
;
Fulan HAN
- Keywords:
bone neoplasms;
desmoplastic fibroma of bone;
clinicopathological features;
histogenesis
- From:
Chinese Journal of Clinical and Experimental Pathology
2017;33(2):153-157
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the clinicopathologic features of desmoplastic fibroma of bone (DF).Methods The clinical and pathologic profiles of 7 cases were retrospectively analyzed.Results Desmoplastic fibroma of bone was a rare neoplasm of bone,which typically occurred in young children and adolescents.The tumor showed infiltrative and locally aggressive nature,the most common sites were long tubular bones and mandible.Microscopically,the tumor was composed of sparse fibroblasts in a rich background of collagen fibers.Immunohistochemically,the tumor cells were positive for vimentin and SMA.Conclusion Desmoplastic fibroma is a rare,locally aggressive fibroblasticlesion of bone.It can make an accurate diagnosis by integrating the clinical location with histopathological features.Trauma,hormone and horomosome aberration may be related with its pathogenesis.
