Evaluation of diuretic and electrolytes excerted effects of Dia Long in experimental animals
- Author:
Tran Thi Hong Thuy
- Publication Type:Journal Article
- Keywords:
Dia Long, diuretic
- MeSH:
Diuretics;
Electrolytes;
animals;
Animal Experimentation
- From:Journal of Medical Research
2003;24(4):25-28
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The experiment was conducted by Lipschitz’s method on white rats of 3 groups, each included 12 animals going without food 18 hours before starting of study. The control group administered orally 1 time only 2ml of water/100g of body mass. The 1st group Dia Long 3g/2ml/100g of body mass, the 2nd group Dia Long 4.5g/2ml/100g of body mass. Rats of all 3 groups were injected subperitoneally 5ml of 0.9% salt solution on 100g of body mass for increasing urine volume. Results showed a diuretic effect of Dia Long, lasting for 6 hours after the use. Dia Long’s excretion effects on Na, K, Cl ions through the kidney were manifested obviously in the 2nd and the fourth hours after use with all the various doses.
