Precision Medicine and Modernization Research on Traditional Chinese Medicine——The Fifth Discussion on the Proposal of Holistic Systems Medicine
10.11842/wst.2017.01.003
- VernacularTitle:精准医学与中医药现代化研究——五论创建新医药学
- Author:
Guoan LUO
;
Yuanyuan XIE
;
Yiming WANG
;
Xuemei FAN
;
Qionglin LIANG
- Keywords:
"Precision medicine;
holistic systems medicine;
traditional Chinese medicine modernization research;
""drug system-biological system"" mode;
integration of formula-disease-syndrome"
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(1):19-29
- CountryChina
- Language:Chinese
-
Abstract:
The origin of precision medicine was discussed in this article,as well as its advantages and deficiencies at this stage.Tangshen formula was taken as an example to explain a rational and ideal mode of traditional Chinese medical (TCM) precision medicine research under the guidance of TCM theory.In view of the two major problems existing in the TCM modernization research,including the separated strategy among formula-disease-syndrome and independent research approach using genomics,proteomics and metabonomics,critical scientific issues on developing the drug system to biological system research mode and solutions for integrating formula-disease-syndrome were proposed here,and the roadmap and total framework of top design were also provided.The specific methods and the corresponding research results on Tangshen formula at the three stages concluded as formula-disease related,disease-syndrome combinated and formula-disease-syndrome integrated were introduced and summarized.At this time for the innovative breakthrough development of TCM,precision medicine will promote the TCM modernization research,and also will provide a powerful driving force for the establishment of holistic systems medicine.
