Comparison of Precise Powder Decoction Pieces and Original Traditional Chinese Medical Slices of Rhizomatic—A Case Study on Fallopia multiflora Radix Preparata
10.11842/wst.2017.01.014
- VernacularTitle:根茎类中药精准煮散饮片探索实例—制何首乌
- Author:
Junqi BAI
;
Zhihai HUANG
;
Juan HUANG
;
Lu GONG
;
Shuiming XIAO
;
Xiwen LI
;
Jiang XU
;
Xiaohui QIU
- Keywords:
Fallopia multiflora radix preparata;
precise powder decoction pieces;
decocting rate;
uniformity
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2017;19(1):95-100
- CountryChina
- Language:Chinese
-
Abstract:
This study aimed at investigating the drug preparation of precise powder decoction pieces (PPDP) system,Fallopia multiflora radix preparata (FMRP) was employed in this study.Different specifications of PPDP were prepared,their extract rates were in contrast with the original pieces.Compared the quality uniformity of three batches between FMRP original slices and its PPDP extraction,the similarity of the chemical fingerprints was evaluated,and the contents of common peaks and quality uniformity were compared by relative peak areas.ITS2 sequence was taken as a DNA barcode to identify F.multiflora radix (FMR).As a result,the extract rate of PPDP was 2.5 times as much as the original slices.The average content of stilbene glucoside from the three original slices and the PPDP extraction were 3.56 ± 2.61 and 13.23 ± 0.37 mg·g-1,respectively;while the RSD were 73.28％ and 2.82％.The similarity of the fingerprints of the PPDP extraction was almost the same as that of the original slices,but the content and the uniformity of the common peaks of the PPDP extraction were significantly improved.Thus,FMR was accurately identified using ITS2 sequences.It was concluded that the PPDP considerably improve the decocting rate and quality uniformity,indicating that PPDP could save resources and improve the clinical efficacy.
