Effects of Different Processing Methods on the Antiosteoporotic Effective Compositions of Psoralea corylifolia L.

VernacularTitle:炮制方法对补骨脂中抗骨质疏松效应成分含量的影响
Author: Na LI ; Dongmei YAN ; Jinlian ZHANG ; Xiumei GAO
Keywords: Psoralea corylifolia L.; processing method; antiosteoporotic composition; effect
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(1):127-132
CountryChina
Language:Chinese
Abstract: This study aimed at evaluating the effect of different processing methods on the contents of antiosteoporotic compositions in P.corylifolia.HPLC method adopted to analyze the contents of antiosteoporotic compositions,including coumarin (psoralen and isopsoralen),flavonoids (neobavaisoflavone,corylifolin,corylifolinin and corylifol A) and meroterpenes (bakuchiol) in P.corylifolia.The contents were analyzed before and after the processing methods.Results:The results showed that the content of coumarin,flavonoids and meroterpenes obviously changed in different processed P.Corylifolia in comparison with the crude drugs.In conclusion,it was demonstrated that the therapeutic efficacy of osteoporosis was enhanced by CP method which increased all of the three compositions.The testimony tallied with the Chinese medical theory:stir-frying with salt-water could enhance the effect of the tonification of spleen and kidney.