Two cases of virus associated hemophagocytic syndrome.
- Author:
Jae Hee HAN
;
Hyun Chul LEE
;
Hwang Min KIM
;
Jong Soo KIM
;
Kyung Won LEE
- Publication Type:Original Article
- Keywords:
Virus associated hemophagocytic syndrome
- MeSH:
Bone Marrow;
Diagnosis;
Fever;
Histiocytosis;
Humans;
Liver;
Lymph Nodes;
Lymphohistiocytosis, Hemophagocytic*;
Pancytopenia
- From:Journal of the Korean Pediatric Society
1993;36(10):1458-1465
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Virus associated hemophagocytic syndrome, class ll histiocytoses, characterized by high fever, severe constitutional symptoms, abnormal liver function and coagulation, perigheral blood pancytopenia and histiocytic hyperplasis with prominent hemophagocytosis in bone marrow and lymph nodes has been reported and associated with active viral infection. It is non-malignant and reversible. It must be differentiated from histiocytic medullary reticulosis because of the inappopriateness of immunosuppressive of cytotozic therapy which is the therapeutic method for HMR, but is contraindicated in the treatment of VAHS. This paper describes two patients whose clinicopathology was compatible with the diagnosis of virus associated hemophagocytic syndrome.
