Clinical effects of Wenxin formula on stable coronary heart disease angina
10.3760/cma.j.issn.1673-4246.2017.05.004
- VernacularTitle:温心方颗粒治疗慢性稳定性心绞痛阳虚痰瘀证临床研究
- Author:
Tongda LI
;
Dongmei LI
;
Wenhui DUAN
;
Wenjing ZONG
;
Huamin ZHANG
;
Hongxin CAO
- Keywords:
Angina;
stable;
Wenxin formula;
Syndrome of Yang deficiency with stagnation of the Blood and retention of Phlegm;
Clinical study
- From:
International Journal of Traditional Chinese Medicine
2017;39(5):397-401
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect and safety of Wenxin formula in the treatment of stable coronary heart disease angina patients with Syndrome of Yang deficiency with stagnation of the Blood and retention of Phlegm (SYBP). Methods A total of 65 stable coronary heart disease angina patients with SYBP were randomly assigned to the trial group and the control group (34 in the trial group and 31 in the control group). The trial group was treated with Wenxin formula, while the control group was treated with atorvastatin. The treatment lasted 4 weeks. The therapeutic effects on angina, reduction of Nitroglycerin, changes of electrocardiogram (ECG) and TCM syndrome score were observed before and after treatment.ResultsAfter treatment, the trial group had a similar effect with the control group in the aspects of the therapeutic effects on angina, reduction of Nitroglycerin and the ECG change. There was no statistical difference between the two groups (P>0.05). The changes of TCM syndrome score in the trial group was superior to the control group (P<0.05). The total effective rates of the trial group and the control group were 88.2% and 74.2%. The significant efficiency of the treatment group (29.41%) was significantly superior to the control group (9.68%) (P<0.05). No adverse reaction occurred during the therapeutic course.Conclusions The Wenxin formula was safe and effective in the treatment of stable coronary heart disease angina patients with SYBP.
