Expression and clinical significance of ARHGAP4 in colorectal cancer
10.3969/j.issn.1006?5725.2017.05.008
- VernacularTitle:ARHGAP4在结直肠癌中的表达及临床意义
- Author:
Xuehu XU
;
Yuandong XU
;
Ziyuan ZHU
;
Shuling LI
;
Xiaobing WU
;
Xuejuan. LIU
- Keywords:
Colorectal cancer;
ARHGAP4
- From:
The Journal of Practical Medicine
2017;33(5):705-708
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression and clinical significance of ARHGAP4 in colorectal cancer Method Real?time PCR,Western blot and immunocytochemistry were used to detect the expression of ARHGAP4 in colorectal cancer tissues and cell lines ,and the correlation between its expression and clinical features of patients was analyzed Results ARHGAP4 is overexpressed in colorectal cancer tissues and cell lines and its overexpression is correlated with T stage, N stage, clinical stage, and metastasis. Conclusion ARHGAP4 may promote the progression of colorectal cancer ,and have the potential to be a novel prognosis marker.
