Correlation between serum uric acid and the severity of coronary borderline lesions in ACS and the prognosis of PCI
10.3969/j.issn.1006-5725.2017.04.016
- VernacularTitle:急性冠脉综合征临界病变血清尿酸及其对PCI预后的影响
- Author:
Jindong WAN
;
Peng ZHOU
;
Jixin HOU
;
Hong CHEN
;
Dengpan LIANG
;
Peijian WANG
- Keywords:
Acute coronary syndrome;
Uric acid;
Coronary borderline lesion;
Percutaneous coronary intervention;
Prognosis
- From:
The Journal of Practical Medicine
2017;33(4):561-564
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the correlation between serum uric acid (SUA) level and the severity of coronary borderline lesions in acute coronary syndrome (ACS) and the prognosis of percutaneous coronary intervention (PCI).Methods The 192 patients who were diagnosed as coronary borderline lesions in ACS and PCI were measured.All Patients were divided into two groups:hyperuricemia group and normal SUA group.The severity of coronary arterial lesions and flow in PCI was compared.The cardiac function changes and incidence of major adverse cardiovascular events (MACE) were recorded.Results The results of correlation analysis showed the positive correlation of SUA level and Gensini score (r =0.710,P ＜ 0.05).Patients with hyperuricemia group had a significantly higher prevalence of no-reflow on angiography,in-hospital and six-month prevalence of MACEs compared with the normal SUA group (P ＜ 0.05).The UA on admission has an independent association with coronary slow flow following primary PCI and in-hospital MACEs among patients with ACS (P ＜ 0.05).Conclusion The patients has higher the level of SUA of ACS borderline lesions patients will has more serious the coronary arterial lesions.The risk of coronary slow flow increased in the patients complicated with hyperuricemia who underwent PCI.
