Primary diffuse large B-cell lymphoma of the heart: a case report and review of the literature

VernacularTitle:原发于心脏弥漫大B细胞淋巴瘤一例并文献复习
Author: Min HU ; Kaifeng YUAN ; Yan CHEN ; Tao MA ; Xiaoming LI
Keywords: Lymphoma; Heart; Primary
From: Chinese Journal of Primary Medicine and Pharmacy 2017;24(8):1190-1193
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical feature,diagnosis,therapy and prognosis of primary cardiac lymphoma.Methods One case of primary diffuse large B-cell lymphoma of the heart was studied.The clinical feature,pathogenesis,diagnosis,therapy and prognosis of primary cardiac lymphoma were further investigated through literatures review.Results Patient,female,64 years old,mainly clinical feature with the activities of chest tightness,gas tight,echocardiogram showed right atrial lesions,ECG of sick sinus syndrome.Right atrial tumor excision by pathological examination confirmed the diagnosis of diffuse large B cell lymphoma(DLBCL),treated with R-CHOP (rituximab,cyclophosphamide,vinorelbine,pirarubicin,prednisone) chemotherapy,cardiac pacemaker implantation,the patient had received 3 cycles of chemotherapy currently,and was at the intermission of chemotherapy.Conclusion Primary cardiac lymphoma is extremely rare.Its pathogenesis remained to be unclear.With non-specific clinical manifestations,the diagnosis is mainly confirmed by histopathological and immunohistochemical staining.It is sensitive to chemotherapy generally,but the special location of the tumor leads to poor prognosis.